Network
Randers FC 1-3 Leicester City*
Gol: 0-1 Harvey Barnes (2), 0-2 James Maddison (70), 0-3 James Maddison (74), 1-3 Stephen Odey (84)
PAOK* 2-1 Midtjylland (PAOK menang adu penalti)
Gol: 1-0 Andrija Zivkovic (20), 2-0 Vieirinha (26), 2-1 Daniel Hoegh (80)
Slavia Prague* 3-2 Fenerbahce
Gol: 1-0 Ivan Schranz (19), 2-0 Yira Sor (27), 2-1 M.H. Yandas (39), 3-1 Yira Sor (63), 3-2 Mergim Berisha (90)
Vitesse* 2-0 Rapid Vienna
Gol: 1-0 Adrian Grbic (3), 2-0 Matus Bero (19)
Kedelapan klub yang lolos babak selanjutnya akan berhadapan dengan LASK, Gent, AS Roma, AZ Alkmaar, Feyenoord, FC Copenhagen, Rennes dan Basel.***
